Is Glutamine Responsible for the Radiosensitivity of Subthalamic Nucleus?
نویسندگان
چکیده
منابع مشابه
Targeting the subthalamic nucleus.
The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN. Our criteria for patient selection and the use of MRI, frame-on CT and volumetric image fusion are presented. T...
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15 صفحه اولFoxa1 is essential for development and functional integrity of the subthalamic nucleus
Inactivation of transcription factor Foxa1 in mice results in neonatal mortality of unknown cause. Here, we report that ablation of Foxa1 causes impaired development and loss of the subthalamic nucleus (STN). Functional deficits in the STN have been implicated in the etiology of Huntington's and Parkinson's disease. We show that neuronal ablation by Synapsin1-Cre-mediated Foxa1 deletion is suff...
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ژورنال
عنوان ژورنال: Stereotactic and Functional Neurosurgery
سال: 2020
ISSN: 1011-6125,1423-0372
DOI: 10.1159/000510889